About
How it works
Every Sunday at 06:00 UTC an automated process searches new scientific publications from PubMed using a curated set of search queries covering ME/CFS, Long COVID, and related mechanisms. Each paper is then scored by Claude Opus – one of the most capable AI models available – on a scale of 1 to 10 for relevance to ME/CFS and PVFS.
Only papers with a score of 4 or higher appear on the website. This includes not only direct ME/CFS studies but also papers from other disciplines – immunology, neurology, mitochondrial research – whose mechanisms may be transferable. That cross-disciplinary perspective is the real value of this system.
Update rhythm
Latest – new papers scored and summarised every Sunday
Treatment Radar – new compounds and drug repurposing findings
Research Gaps – open questions and hypotheses for further study
Foundations – curated core literature from 2019 to today
Using this site as a research tool
Use the bookmark icon on any article to build a personal collection. When ready, click "Copy for AI" in the collection panel – this generates a structured prompt with all saved articles that you can paste directly into an AI assistant.
Recommended AI tools
Claude (claude.ai) – particularly strong with medical and scientific texts
ChatGPT (chatgpt.com) – widely available, good for initial questions
Perplexity (perplexity.ai) – good for research with direct source references
Scoring criteria
Study explicitly addresses ME/CFS, PVFS or Long COVID fatigue
Study addresses a known mechanism in another context – clearly transferable
Hypothetical relevance – theoretical connection to a known mechanism
Not shown – no recognizable connection to known mechanisms
Get in touch
This site is continuously evolving. If you have suggestions, want to contribute a study or interview, or simply want to get in touch:
mecfsresearch@proton.meResponse times may vary – this is a one-person project.
⚠️ Disclaimer
All content on this website is AI-generated based on scientific literature. It does not constitute medical advice, replace a medical diagnosis or represent treatment recommendations. For health questions always consult qualified medical professionals.