About

How it works

Every Sunday an automated process searches new scientific publications from PubMed using a curated set of search queries covering ME/CFS, Long COVID, and related mechanisms. Each paper is then scored by Claude Opus on a scale of 1 to 10 for relevance to ME/CFS and PVFS.

Only papers with a score of 4 or higher appear on the website. This includes not only direct ME/CFS studies but also papers from other disciplines like immunology, neurology, mitochondrial research, whose mechanisms may be transferable. That cross disciplinary perspective is the real value of this system.

Update rhythm

Weekly

Latest – new papers scored and summarised every Sunday

Bi-weekly

Treatment Radar – new compounds and drug repurposing findings

Monthly

Lab Guide – guide for laboratory research and diagnostics

Quarterly

Foundations – curated core literature from 2019 to today

Using this site as a research tool

Use the bookmark icon on any article to build a personal collection. When ready, click "Copy for AI" in the collection panel, this generates a structured prompt with all saved articles that you can paste directly into an AI assistant.

Recommended AI tools

Claude (claude.ai) – particularly strong with medical and scientific texts

ChatGPT (chatgpt.com) – widely available, good for initial questions

Perplexity (perplexity.ai) – good for research with direct source references

Scoring criteria

8–10

Direct relevance to ME/CFS

5–7

Transferable mechanisms

4

Theoretical relevance

1–3

No recognizable connection

Get in touch

This site is continuously evolving. If you have suggestions, want to contribute a study or interview, or simply want to get in touch:

mecfsresearch@proton.me

Response times may vary, as this is a one person project.

⚠️ Disclaimer

All content on this website is AI generated based on scientific literature. It does not constitute medical advice, replace a medical diagnosis or represent treatment recommendations. For health questions always consult qualified medical professionals.